About Department
   
Department Home
Department Profile
Director Message
Academic
Reasearch Profile
Faculty & Staff Members
Admissions
Syllabus
Student Information
Contact Information
 

Research Grants sanctioned during last five years

DBT, Govt. of India

  • M.Sc. Bioinformatics program at SPPU Pune supported by HRD-DBT, INR 363.6 Lakh, 2020-25
  • Establishment of Bioinformatics and Computational Biology Centre for Viral Bioinformatics, INR 249.45 Lakh, 2021-26 PIs: Dr. Urmila Kulkarni-Kale, Dr. Sangeeta Sawant. Project Co-PIs: Dr. Manali Joshi, Dr. Abhijeet Kulkarni, Dr. Payel Ghosh, Dr. Rohan Meshram, Dr. Vijay Baladhye, Mr. Dattatraya Desai, Ms. Smita Saxena, Mr. Sanjay Londhe
  • Identification of lead molecules for development of novel therapeutic strategies against viruses, INR 242.715 Lakh 2022-27 PIs: Dr. Sangeeta Sawant, Dr. Manali Joshi. Collaboration with Dr. Deepak Nair, Dr. Sudhanshu Vrati (RCB) and Dr. Shailendra Asthana (THSTI) under NNP funded by DBT, GoI
  • Method development for extraction of herbal gamma-aminobutyric acid (GABA) from Pandanus odorifer L, INR 39.98 Lakh, 2022-25, Co-I: Dr. Abhijeet Kulkarni
  • Indian Medicinal Plants Genome Initiative, PC: Hon. VC, Mentor: Dr. Shekhar Mande, PI: Dr. Abhijeet Kulkarni, CoI: Dr. Manali Joshi. Dr. Payel Ghosh, Ms. Smita Saxena, Dr. Girish Tillu, Dr. Preeti Chauhan-Gautam ( DBT-SAHAJ grant, INR 1984.27132 Lakh)
DST SERB, Govt. of India
  • Deciphering the molecular mechanism underlying the anti-adipogenic activity of Inonotus exudate, INR 27.416 Lakh, 2023-26, Co-PI: Dr. Abhijeet Kulkarni
DST FIST, Govt. of India
  • FIST Program-2024, INR 78.75 Lakh, 2025-30
ICMR, Govt. of India
  • Scaffold-based 3D in vitro non-alcoholic fatty liver disease (NAFLD) model for high throughput drug screening, INR 53 Lakh, 2023-26, Co-I: Dr. Payel Ghosh
  • Comprehensive Drug Sensitivity and Genomic Profiling of Cancer Tumors, INR 531.89 Lakh, 2025-28, Co-I: Dr. Abhijeet Kulkarni
  • Epigenetic and pharmacogenetic assessment of toxicity and outcome after platinum plus taxane based chemotherapy in breast cancer patients, INR 60.841 Lakh, 2025-28, Co-I: Dr. Abhijeet Kulkarni
ANRF Grant
  • A multiversity alliance on health and energy through engineered biomolecular systems INR 2.3 Cr; 2025-26. Co-I: Dr. Manali Joshi, Dr. Abhijeet Kulkarni, Dr. Payel Ghosh, Dr. Rohan Meshram
 Publications during last five years
  1. Vaidya SR, Sharma S, Kamble MB, Sreedeep KS, Deepthi B, Kulkarni S, Gade S, Pandey PG, Joshi M, Divatia J, Dhamne CA. Clinico-virological investigation of measles complications in immunocompromised pediatric patients. Infect Genet Evol. 2026 Mar 5;139:105918. doi: 10.1016/j.meegid.2026.105918. Epub ahead of print. PMID: 41794164.
  2. Anjulal H, Saha A, Barvkar VT, Pawar K, Joshi M, Zinjarde SS. Overexpression, biochemical characterization, and structural modeling of polyhydroxybutyrate depolymerase from Nocardiopsis dassonvillei. Enzyme Microb Technol. 2026 Feb;193:110767. doi: 10.1016/j.enzmictec.2025.110767. Epub 2025 Oct 25. PMID: 41151231.
  3. Doiphode S, Ghosh P, Swamy KV, Nagar S. An In Silico Study of Resveratrol Derivatives as Dual Inhibitors of Cyclooxygenase-2 (COX-2) and 5-Lipoxygenase (5-LOX) in Cancer Therapy. Biotechnol Appl Biochem. 2026 Feb 20. doi: 10.1002/bab.70150. Epub ahead of print. PMID: 41721494.
  4. Jagtap RA, Jagdale BS, Dhonnar SL, Shaikh SA, More RA, Alavala RR, Muteeb G, Fernandez-Conde D, Pawar TJ, Meshram RJ, Escobar-Cabrera J, Chobe SS. Efficient synthesis, dual anti-tubercular and antioxidant activity of triazole-acetophenone derivatives: enhanced efficacy via esterification and quantum mechanical validation of CYP121 binding. RSC Adv. 2026 Jan 15;16(4):3609-3622. doi: 10.1039/d5ra09368f. PMID: 41550807; PMCID: PMC12805941.
  5. Shaikh SA, Wakchaure SN, Meshram RJ, Deokar SC, More RA, Nerkar CK, Chobe SS. Resynthesis, Antimicrobial Evaluation and Molecular Docking Studies of Thiazolyl-2-Chloroacetamide Derivatives as Potential Broad-Spectrum Agents. Chem Biodivers. 2025 Nov;22(11):e01486. doi: 10.1002/cbdv.202501486. Epub 2025 Jun 25. PMID: 40566849.
  6. Mahajan P, Gor H, Joshi M, Nema V. DapB is a conserved target for tackling antimicrobial resistance in Mycobacterium tuberculosis. J Biomol Struct Dyn. 2025 Nov 6:1-12. doi: 10.1080/07391102.2025.2581074. Epub ahead of print. PMID: 41197090.
  7. R. Wakade, R. Thakur, S. Saxena and M. Joshi, "Network Pharmacology and Enrichment Analysis Reveal Reproductive and Systemic Wellness Benefits of Glycyrrhiza Glabra and Asparagus Racemosus," 2025 IEEE Pune Section International Conference (PuneCon), Pune, India, 2025, pp. 1-6, doi: 10.1109/PuneCon67554.2025.11379791.
  8. V. Verma, V. Pokhrel, B. K. Kuntal and P. Ghosh, "Analysis of Phage-Bacteria-Food Association and its Relation to Human Health Using Knowledge Graphs," 2025 IEEE Pune Section International Conference (PuneCon), Pune, India, 2025, pp. 1-6, doi: 10.1109/PuneCon67554.2025.11377613.
  9. S. Patil, A. Sur, A. Gotkhindikar and M. Joshi, "Machine Learning Based Approach for GPCR Ligand Binding Prediction: A First Step Towards Deorphanization," 2025 IEEE Pune Section International Conference (PuneCon), Pune, India, 2025, pp. 1-5, doi: 10.1109/PuneCon67554.2025.11378902.
  10. Matairesinol Targets Lipid Metabolism Reprogramming in AR-Independent Prostate Cancer Cells. Mahajan M, Ghodke G, Joshi M, Chaudhary A, Kaul-Ghanekar R. Asian Pac J Cancer Prev. 2025 Aug 1;26(8):2855-2867. doi: 10.31557/APJCP.2025.26.8.2855.
  11. Host-Directed Therapeutic for the treatment of Mycobacterium tuberculosis. Mahajan P, Gor HR, Jadhav S, Joshi M, Nema V. Microbiol Res. 2025 Oct;299:128253. doi: 10.1016/j.micres.2025.128253.
  12. Skin lesion classification using convolutional neural networks. S Patel, S Saxena. Int. J. Adv. Res. Comput. Sci. 2025 June 10;16 (3), 104-108. doi: 10.26483/ijarcs.v16i3.7284
  13. Reverse vaccinology-based design of multivalent multiepitope mRNA vaccines targeting key viral proteins of Herpes Simplex Virus type-2. Suneesh NS, Dhotre K, Mahajan P, Dass D, Banerjee A, Siddiqi NJ, Malik A, Joshi M, Khan AA, Nema V, Mukherjee A. Front Immunol. 2025 May 20;16:1586271. doi: 10.3389/fimmu.2025.1586271.
  14. Genomic and functional insights into the diversity of Capsicum annuum defensin gene family. Mulla JA, Palod PS, Bhagwat SA, Sonawane AP, Acharya SK, Kulkarni AP, Tamhane VA. 3 Biotech. 2025 Apr;15(4):99. doi: 10.1007/s13205-025-04256-y.
  15. Resynthesis, Antimicrobial Evaluation and Molecular Docking Studies of Thiazolyl-2-Chloroacetamide Derivatives as Potential Broad-Spectrum Agents. Shaikh SA, Wakchaure SN, Meshram RJ, Deokar SC, More RA, Nerkar CK, Chobe SS. Chem Biodivers. 2025 Jun 25:e01486. doi: 10.1002/cbdv.202501486.
  16. Jani V, Sonavane U, Sawant S. Structural insights into the activation mechanism of phosphoinositide 3-kinase alpha. Comput Biol Chem. 2024 Feb;108:107994. doi: 10.1016/j.compbiolchem.2023.107994. Epub 2023 Nov 30. PMID:38043374.
  17. Kamble, S.C., Ghosh, P.D. Defining omics-based biomarker signatures of metabolic dysfunction-associated steatotic liver disease (MASLD): In vitro studies. Current Opinion in Biomedical Engineering, 2024, 30, 100534. ISSN(print/online): 2468-4511, URL/DOI: http://dx.doi.org/10.1016/j.cobme.2024.100534
  18. Singh, S., Ghosh, P., Sharma, S., Bhargava, S., Kumar, A.R. Tetrahydropalmatine from medicinal plants activates human glucokinase to regulate glucose homeostasis. Biotechnology and Applied Biochemistry, 2024, 71 (2), 295-313. ISSN(print/online): 0885-4513/1470-8744, URL/DOI: http://dx.doi.org/10.1002/bab.2541
  19. Nikte, S.V., Joshi, M., Sengupta, D. State-dependent dynamics of extramembrane domains in the β2-adrenergic receptor. Proteins: Structure, Function and Bioinformatics, 2024, 92 (3), 1-12. ISSN(print/online): 0887-3585/1097-0134, URL/DOI: http://dx.doi.org/10.1002/prot.26613
  20. Bose, G.S., Kalakoti, G., Kulkarni, A.P., Mittal, S. AP-1/C-FOS and AP-1/FRA2 differentially regulate early and late adipogenic differentiation of mesenchymal stem cells. Journal of Cellular Biochemistry, 2024. ISSN(print/online): 0730-2312/1097-4644, URL/DOI: http://dx.doi.org/10.1002/jcb.30543
  21. Gire, D., Inamdar, S., Acharya, J., Sadawarte, S., Kulkarni, A., Ghaskadbi, S. Dynamic changes in the gene expression during adipogenesis in hMSCs. Genetic Resources and Crop Evolution, 2024, 34, 101860. ISSN(print/online): 0925-9864/1573-5109, URL/DOI: http://dx.doi.org/10.1016/j.genrep.2023.101860
  22. Limaye, S., Shelke, A., Kale, M.M., Kulkarni-Kale, U., Kuchipudi, S.V. IDV Typer: An Automated Tool for Lineage Typing of Influenza D Viruses Based on Return Time Distribution. Viruses, 2024. 16 (3), 373. ISSN(print/online): 1999-4915, URL/DOI: http://dx.doi.org/10.3390/v16030373
  23. Shaikh, S.A., Pachorkar, P.Y., Meshram, R.J., Boraste, D.R., More, R.A., Chobe, S.S., Ballabh, D., Wakchaure, S.N., Labhade, S.R., Kale, R.R., Labhade, H.S. Synthesis, Biological and Molecular Docking Studies of Thiazole-Thiadiazole derivatives as potential Anti-Tuberculosis Agents. Chemistry and Biodiversity, 2024. ISSN(print/online): 1612-1872/1612-1880, URL/DOI: http://dx.doi.org/10.1002/cbdv.202400496
  24. Ballav S, Lokhande KB, Yadav RS, Ghosh P, Swamy KV, Basu S. Exploring binding mode assessment of novel kaempferol, resveratrol, and quercetin derivatives with PPAR-α as potent drug candidates against cancer. Mol Divers. 2023 Dec;27(6):2867-2885. doi: 10.1007/s11030-022-10587-2. PMID: 36544031.
  25. Lin SJ, Vona B, Lau T, Huang K, Zaki MS, Aldeen HS, Karimiani EG, Rocca C, Noureldeen MM, Saad AK, Petree C, Bartolomaeus T, Abou Jamra R, Zifarelli G, Gotkhindikar A, Wentzensen IM, Liao M, Cork EE, Varshney P, Hashemi N, Mohammadi MH, Rad A, Neira J, Toosi MB, Knopp C, Kurth I, Challman TD, Smith R, Abdalla A, Haaf T, Suri M, Joshi M, Chung WK, Moreno-De-Luca A, Houlden H, Maroofian R, Varshney GK. Evaluating the association of biallelic OGDHL variants with significant phenotypic heterogeneity. Genome Med. 2023 Nov 29;15(1):102. doi: 10.1186/s13073-023-01258-4. PMID: 38031187; PMCID: PMC10688095.
  26. Vaidya SR, Kumbhar NS, Andhare GK, Pawar N, Walimbe AM, Kinikar M, Kasibhatla SM, Kulkarni-Kale U. Neutralizing Antibody Response to Genotypically Diverse Measles Viruses in Clinically Suspected Measles Cases. Viruses. 2023 Nov 10;15(11):2243. doi: 10.3390/v15112243. PMID: 38005920; PMCID: PMC10674322.
  27. Doiphode S, Lokhande KB, Ghosh P, Swamy KV, Nagar S. Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) by resveratrol derivatives in cancer therapy: in silico approach. J Biomol Struct Dyn. 2023 Oct- Nov;41(17):8571-8586. doi: 10.1080/07391102.2022.2135599. PMID: 36282056.
  28. Sawant P, Kulkarni A, Mane R, Patil R, Lavania M. Metatranscriptomic assessment of diarrhoeic faeces reveals diverse RNA viruses in rotavirus group A infected piglets and calves from India. Front Cell Infect Microbiol. 2023 Oct 27;13: 1258660. doi: 10.3389/fcimb.2023.1258660. PMID: 37965252; PMCID: PMC10642067.
  29. Saxena, A., Saxena, S. (2023). Pancreatic Cancer Data Classification with Quantum Machine Learning. Journal of Quantum Computing, 5 (1), 1-13. ISSN(print/online): 2579-0137/2579-0145, URL/DOI: http://dx.doi.org/10.32604/jqc.2023.044555
  30. Gedam PA, Khandagale K, Shirsat D, Thangasamy A, Kulkarni O, Kulkarni A, Patil SS, Barvkar VT, Mahajan V, Gupta AJ, Bhagat KP, Khade YP, Singh M, Gawande S. Elucidating the molecular responses to waterlogging stress in onion (Allium cepa L.) leaf by comparative transcriptome profiling. Front Plant Sci. 2023 Aug 8;14: 1150909. doi: 10.3389/fpls.2023.1150909. PMID: 37615019; PMCID: PMC10442827.
  31. Patil AM,Lagad PM,Soge B,Meshram RJ,Lokhande MN, Lokhande PD. Ammonium chloride mediated synthesis of 2-aryl-phthalazinone from O-formyl benzoic acid and in silico applications. Arkivoc May 2023 (vii) 202311972 DOI:10.24820/ark.5550190.p011.972
  32. Lodha K, Wavhal D, Bhujbal N, Mazire P, Bhujbal S, Korde A, Bagul K, Roy A, Meshram R, Shinde V. Synthesis and biological evaluation of 9-aryl-1, 8-dioxo-octahydroxanthene derivatives as antileishmanial agents. Results in Chemistry, April 2023, 5, 100943, DOI:10.1016/j.rechem.2023.100943
  33. Chand K, Barman MK, Ghosh P, Mitra D. DNAJB8 facilitates autophagic-lysosomal degradation of viral Vif protein and restricts HIV-1 virion infectivity by rescuing APOBEC3G expression in host cells. FASEB J. 2023 Mar;37(3):e22793. doi:10.1096/fj.202201738R. PMID: 36723955.
  34. Lokhande KB, Pawar SV, Madkaiker S, Nawani N, Venkateswara SK, Ghosh P. High throughput virtual screening and molecular dynamics simulation analysis of phytomolecules against BfmR of Acinetobacter baumannii: anti-virulent drug development campaign. J Biomol Struct Dyn. 2023Apr;41(7):2698-2712. doi:10.1080/07391102.2022.2038271. Epub 2022 Feb 14. PMID: 35156902.
  35. Lokhande KB, Banerjee T, Swamy KV, Ghosh P, Deshpande M. An in silico scientific basis for LL-37 as a therapeutic for Covid-19. Proteins. 2022 May;90(5):1029-1043. doi: 10.1002/prot.26198. Epub 2021 Aug 9. PMID: 34333809; PMCID: PMC8441666.
  36. Yadav S, Raazi Z, Shivaraj SM, Somani D, Prashant R, Kulkarni A, Kumar R,Biradar S, Desai S, Kadoo N. Whole Genome Sequencing and Comparative Genomics of Indian Isolates of Wheat Spot Blotch Pathogen Bipolaris sorokiniana Reveals Expansion of Pathogenicity Gene Clusters. Pathogens. 2022 Dec 20;12(1):1. doi: 10.3390/pathogens12010001. PMID: 36678349; PMCID: PMC9865733.
  37. Hufsky F, Abecasis A, Agudelo-Romero P, Bletsa M, Brown K, Claus C, Deinhardt-Emmer S, Deng L, Friedel CC, Gismondi MI, Kostaki EG, Kühnert D, Kulkarni-Kale U, Metzner KJ, Meyer IM, Miozzi L, Nishimura L, Paraskevopoulou S, Pérez-Cataluña A, Rahlff J, Thomson E, Tumescheit C, van der Hoek L, Van Espen L, Vandamme AM, Zaheri M, Zuckerman N, Marz M. Women in the European Virus Bioinformatics Center. Viruses. 2022 Jul 12;14(7):1522. doi: 10.3390/v14071522. PMID: 35891501; PMCID: PMC9319252.
  38. Mane A, Kasibhatla SM, Vidhate P, Saxena V, Patil S, Rao A, Nirmalkar A, Kulkarni-Kale U, Panda S. Phylogenetic Analysis of Spread of Hepatitis C Virus Identified during HIV Outbreak Investigation, Unnao, India. Emerg Infect Dis. 2022 Apr;28(4):725-733. doi: 10.3201/eid2804.211845. PMID: 35318918; PMCID: PMC8962895.
  39. Mane A, Limaye S, Patil L, Kulkarni-Kale U. Genetic variability in minor capsid protein (L2 gene) of human papillomavirus type 16 among Indian women. Med Microbiol Immunol. 2022 Jun;211(2-3):153-160. doi: 10.1007/s00430-022-00739-4. Epub 2022 May 13. PMID: 35552511; PMCID: PMC9101989.
  40. Khandagale K, Roylawar P, Kulkarni O, Khambalkar P, Ade A, Kulkarni A, Singh M, Gawande S. Comparative Transcriptome Analysis of Onion in Response to Infection by Alternaria porri (Ellis) Cifferi. Front Plant Sci. 2022 Apr 11;13:857306. doi: 10.3389/fpls.2022.857306. PMID: 35481153; PMCID: PMC9036366.
  41. Joshi S, Ghosh P, Barage S, Basu B, Deobagkar DD. Genome-wide lone strand adenine methylation in Deinococcus radiodurans R1: Regulation of gene expression through DR0643-dependent adenine methylation. Microbiol Res. 2022 Apr;257:126964. doi:10.1016/j.micres.2022.126964.
  42. Paithankar H, Tarang GS, Parvez F, Marathe A, Joshi M, Chugh J. Inherent conformational plasticity in dsRBDs enables interaction with topologically distinct RNAs. Biophys J. 2022 Mar15;121(6):1038-1055.
  43. Joshi M, Nikte SV, Sengupta D. Molecular determinants of GPCR pharmacogenetics: Deconstructing the population variants in β2-adrenergic receptor. Adv Protein Chem Struct Biol. 2022;128:361-396. doi: 10.1016/bs.apcsb.2021.08.002. Epub 2021 Oct 13. PMID:35034724.
  44. Rohit P. Kamble, Payel Ghosh, Anjali A. Kulkarni, Identification of α-amylase inhibitory compounds from leaves of Careya arborea Roxb. and in silico docking studies, South African Journal of Botany, 2022, ISSN 0254-6299, https://doi.org/10.1016/j.sajb.2022.05.018.
  45. Meshram RJ, Kathwate GH, Gacche RN. Progress, evolving therapeutic/diagnostic approaches, and challenges in the management of hepatitis C virus infections. Arch Virol. 2022 Jan 28:1–20. doi: 10.1007/s00705-022-05375-0. Epub ahead of print. PMID: 35089390; PMCID: PMC8795940.
  46. Lodha, K.K., Wavhal, D.S., Bhalekar, S.B., Meshram, R.J., Shinde, V.S. (2022). Exploring New Tetrahydrothienopyridine Derivatives as Platelet Agglutination Inhibitors: Synthesis, Biological Evaluation and In Silico Study. ChemistrySelect, 7 (2), 202103428. ISSN(print/online): 2365-6549, URL/DOI: http://dx.doi.org/10.1002/slct.202103428
  47. Mane A, Limaye S, Patil L, Kulkarni-Kale U. Genetic variations in the long control region of human papillomavirus type 16 isolates from India: implications for cervical carcinogenesis. J Med Microbiol. 2022 Jan;71(1). doi:10.1099/jmm.0.001475. PMID: 35040427.
  48. Gokavi J, Sadawarte S, Shelke A, Kulkarni-Kale U, Thakar M, Saxena V. Inhibition of miR-155 Promotes TGF-ß Mediated Suppression of HIV Release in the Cervical Epithelial Cells. Viruses. 2021 Nov 12;13(11):2266. doi: 10.3390/v13112266. PMID: 34835072
  49. Kulkarni AS, Ramesh R, Walia S, Sayyad SI, Gathalkar GB, Balamkundu S, Joshi M, Sen A, Reddy DS. Identification of a Novel Series of Potent Organosilicon Mosquito Repellents. ACS Omega. 2021 Nov 12;6(46):31236-31243. doi: 10.1021/acsomega.1c04961. PMID: 34841167; PMCID: PMC8613865.
  50. Limaye S, Kasibhatla SM, Ramtirthkar M, Kinikar M, Kale MM, Kulkarni-Kale U. Circulation and Evolution of SARS-CoV-2 in India: Let the Data Speak. Viruses. 2021 Nov 8;13(11):2238. doi: 10.3390/v13112238. PMID: 34835044
  51. Lin SJ, Vona B, Barbalho PG, Kaiyrzhanov R, Maroofian R, Petree C, Severino M, Stanley V, Varshney P, Bahena P, Alzahrani F, Alhashem A, Pagnamenta AT, Aubertin G, Estrada-Veras JI, Hernández HAD, Mazaheri N, Oza A, Thies J, Renaud DL, Dugad S, McEvoy J, Sultan T, Pais LS, Tabarki B, Villalobos-Ramirez D, Rad A; Genomics England Research Consortium, Galehdari H, Ashrafzadeh F, Sahebzamani A, Saeidi K, Torti E, Elloumi HZ, Mora S, Palculict TB, Yang H, Wren JD, Ben Fowler, Joshi M, Behra M, Burgess SM, Nath SK, Hanna MG, Kenna M, Merritt JL 2nd, Houlden H, Karimiani EG, Zaki MS, Haaf T, Alkuraya FS, Gleeson JG, Varshney GK. Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish. Genet Med. 2021 Oct;23(10):1933-1943. doi: 10.1038/s41436-021-01239-1. Epub 2021 Jun 25.PMID: 34172899
  52. Lokhande KB, Ghosh P, Nagar S, Venkateswara Swamy K. Novel B, C-ring truncated deguelin derivatives reveals as potential inhibitors of cyclin D1 and cyclin E using molecular docking and molecular dynamic simulation. Mol Divers. 2021 Oct 9. doi: 10.1007/s11030-021-10334-z. Epub ahead of print. PMID:34626304.
  53. Meshram RJ, Bagul KT, Aouti SU, Shirsath AM, Duggal H, Gacche RN. Modeling and simulation study to identify threonine synthase as possible drug target in Leishmania major. Mol Divers. 2021 Aug;25(3):1679-1700. doi:10.1007/s11030-020-10129-8. Epub 2020 Jul 31. PMID: 32737682.
  54. González-Candelas F, Shaw MA, Phan T, Kulkarni-Kale U, Paraskevis D, Luciani F, Kimura H, Sironi M. One year into the pandemic: Short-term evolution of SARS-CoV-2 and emergence of new lineages. Infect Genet Evol. 2021 Aug;92:104869. doi:10.1016/j.meegid.2021.104869. Epub 2021 Apr 26. PMID: 33915216; PMCID:PMC8074502.
  55. Roy A, Behera S, Mazire PH, Kumari B, Mandal A, Purkait B, Ghosh P, Das P, Das P. The HIV - 1 protease inhibitor Amprenavir targets Leishmania donovani topoisomerase I and induces oxidative stress-mediated programmed cell death. Parasitol Int. 2021 Jun;82:102287. doi: 10.1016/j.parint.2021.102287. Epub 2021 Jan 27. PMID: 33515743.
  56. Sawant AS, Kamble SS, Pisal PM, Sawant SS, Hese SV, Bagul KT, Pinjari RV, Kamble VT, Meshram RJ, Gacche RN. Synthesis and evaluation of N-(4-(substituted)-3-(trifluoromethyl) phenyl) isobutyramides and their N-ethyl analogous as anticancer, anti-angiogenic & antioxidant agents: In vitro and in silico analysis. Comput Biol Chem. 2021 Jun;92:107484. doi:10.1016/j.compbiolchem.2021.107484. Epub 2021 Apr 8. PMID: 33865034.
  57. Gujar N, V Nikte S, Joshi RS, Joshi M. Molecular Characterization of the β 2-like Octopamine Receptor of Helicoverpa armigera. J Membr Biol. 2021 Jun;254(3):311-319. doi: 10.1007/s00232-021-00172-3. Epub 2021 Feb 11. PMID: 33570689.
  58. Borse S, Joshi M, Saggam A, Bhat V, Walia S, Marathe A, Sagar S, Chavan-Gautam P, Girme A, Hingorani L, Tillu G. Ayurveda botanicals in COVID-19 management: An in silico multi-target approach. PLoS One. 2021 Jun 11;16(6):e0248479. doi: 10.1371/journal.pone.0248479. PMID: 34115763; PMCID:PMC8195371.
  59. Kolhe N, Kulkarni A, Zinjarde S, Acharya C. Transcriptome Response of the Tropical Marine Yeast Yarrowia lipolytica on Exposure to Uranium. Curr Microbiol. 2021 May;78(5):2033-2043. doi: 10.1007/s00284-021-02459-z. Epub 2021 Mar 27. PMID: 33772621.
  60. Kharche S, Joshi M, Chattopadhyay A, Sengupta D. Conformational plasticity and dynamic interactions of the N-terminal domain of the chemokine receptor CXCR1. PLoS Comput Biol. 2021 May 20;17(5):e1008593.doi:10.1371/journal.pcbi.1008593. PMID: 34014914; PMCID: PMC8172051.
  61. Nikte SV, Sonar K, Tandale A, Joshi M, Sengupta D. Loss of a water-mediated network results in reduced agonist affinity in a β2-adrenergic receptor clinical variant. Biochim Biophys Acta Proteins Proteom. 2021 Apr;1869(4):140605. doi: 10.1016/j.bbapap.2021.140605. Epub 2021 Jan 14. PMID: 33453412.
  62. Alai S, Gujar N, Joshi M, Gautam M, Gairola S. Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike protein. Heliyon. 2021 Mar;7(3):e06564. doi: 10.1016/j.heliyon.2021.e06564. Epub 2021 Mar 19. PMID: 33758785; PMCID: PMC7972664.
  63. Vaidya SR, Kasibhatla SM, Kamble MB, Munivenkatappa A, Kumbhar NS, Jayaswamy MM, Ramtirthkar MR, Kale MM, Kulkarni-Kale U. Genetic and antigenic characterization of wild type rubella viruses isolated from India. Vaccine. 2021 Feb 5;39(6):876-881. doi: 10.1016/j.vaccine.2020.12.063. Epub 2021 Jan 8. PMID: 33423836.
  64. Dar MS, Dholakia BB, Kulkarni AP, Oak PS, Shanmugam D, Gupta VS, Giri AP. Influence of domestication on specialized metabolic pathways in fruit crops. Planta. 2021 Feb 4;253(2):61. doi: 10.1007/s00425-020-03554-4. PMID: 33538903.
  65. Dandekar PD, Kotmale AS, Chavan SR, Kadlag PP, Sawant SV, Dhavale DD, RaviKumar A. Insights into the Inhibition Mechanism of Human Pancreatic α-Amylase, a Type 2 Diabetes Target, by Dehydrodieugenol B Isolated from Ocimum tenuiflorum. ACS Omega. 2021 Jan 13;6(3):1780-1786. doi:10.1021/acsomega.0c00617. PMID: 33521419; PMCID: PMC7841778.
  66. Kadam K, Peerzada N, Karbhal R, Sawant S, Valadi J, Kulkarni-Kale U. Antibody Class(es) Predictor for Epitopes (AbCPE): A Multi-Label Classification Algorithm. Front Bioinform. 2021 Sep 7;1:709951. doi: 10.3389/fbinf.2021.709951. PMID: 36303781; PMCID: PMC9581038.
 Granted Patent details:
  1. Indian Patent granted for “A method for identifying the selective inhibitors of human DNA methyltransferase1 (hDNMT1)” on 21/02/2024 under patent no. 513408. (Dr. Manali Joshi)
  2. A patent granted by the Japan Patent Office. on 27/02/2024 for "DAF-MCP chimeric proteins, process to manufacture the same and use of the chimeric protein for treating pathological conditions involving the complement system" under patent no. 7444968. (Dr. Payel Ghosh)
  3. International patent granted in the Republic of South Africa with effect from 28 Feb 2024 for Method Preparing chelated different amino acids from garlic turpale waste. Patent number 2023/06867 (Dr. Rohan Meshram)
  4. International patent granted in the Republic of South Africa with effect from 28 Feb 2024 for “A method to identify and synthesize suitable T-cell epitopes on E1 glycoprotein as potential subunit vaccine Candidates against hepatitis C”. Patent number 023/09751. (Dr. Rohan Meshram)

 

 

 

 

Copyright © 2010-11 University of Pune. All Rights Reserved.